METABOLISM OF METHYLSCOPOLAMMONIUM METHYLSULFATE (DD-234) IN RATSSANO M; HAKUSUI H.1974; CHEM. PHARM. BULL.; JAP.; DA. 1974; VOL. 22; NO 3; PP. 696-706; BIBL. 12 REF.Article

BIOTRANSFORMATION OF CHLORMEZANONE, 2-(4-CHLORO-PHENYL)-3-METHYL-4-METHATHIAZANONE-1,1-DIOXIDE, A MUSCLE-RELAXING AND TRANQUILLIZING AGENT: THE EFFECT OF COMBINATION WITH ASPIRIN ON ITS METABOLIC IN RATS AND MICE.HAKUSUI H; TACHIZAWA H; SANO M et al.1978; XENOBIOTICA; G.B.; DA. 1978; VOL. 8; NO 4; PP. 229-238; BIBL. 4 REF.Article

MASS FRAGMENTOGRAPHIC DETERMINATION OF LOFEPRAMINE AND ITS METABOLITES IN HUMAN PLASMA AND URINE USING DEUTERATED INTERNAL STANDARDS.MATSUBAYASHI K; HAKUSUI H; SANO M et al.1977; J. CHROMATOGR.; NETHERL.; DA. 1977; VOL. 143; NO 6; PP. 571-580; BIBL. 17 REF.Article

STUDIES ON PHARMACOKINETICS AND BIOTRANSFORMATION OF OXEPINAC IN MOUSE, RAT, DOG AND MAN.HAKUSUI H; SUZUKI W; TAKEGOSHI T et al.1978; ARZNEIMITTEL-FORSCH.; DTSCH.; DA. 1978; VOL. 28; NO 3; PP. 456-461; ABS. ALLEM.; BIBL. 13 REF.Article

Mechanism of the formation of S-glucuronide in malotilate metabolismNAKAOKA, M; HAKUSUI, H.Journal of pharmacobio-dynamics. 1990, Vol 13, Num 4, issn 0386-846X, p. s.69Conference Paper

Identification of two major biliary metabolites of carvedilol in ratsFUJIMAKI, M; HAKUSUI, H.Xenobiotica (London. Print). 1990, Vol 20, Num 10, pp 1025-1034, issn 0049-8254, 10 p.Article

SYNTHETIC STUDIES ON ANTHRACYCLINONES. X. SYNTHESIS OF METHYL 2-(1-ACETOXY-3-OXOBUTYL) PHENYLACETATE)HORII ZI; HAKUSUI H; SHIGEUCHI T et al.sdYAKUGAKU ZASSHI, J. PHARM. SOC. JAP.; JAP.; DA. )197; VOL. 92; NO 4; PP. 503-506; ABS. ANGLSerial Issue

Pharmacokinetics of SN-38 [(+)-(4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione], an active metabolite of irinotecan, after a single intravenous dosing of ¹⁴C-SN-38 to ratsATSUMI, R; OKAZAKI, O; HAKUSUI, H et al.Biological & pharmaceutical bulletin. 1995, Vol 18, Num 8, pp 1114-1119, issn 0918-6158Article

Interaction of quinolones with metal cations in aqueous solutionKAWAI, Y; MATSUBAYASHI, K; HAKUSUI, H et al.Chemical and pharmaceutical bulletin. 1996, Vol 44, Num 8, pp 1425-1430, issn 0009-2363Article

Biliary metabolites of semotiadil fumarate in the ratNAKAOKA, M; KATOH, K; HAKUSUI, H et al.Xenobiotica (London. Print). 1995, Vol 25, Num 8, pp 847-855, issn 0049-8254Article

Isolation and identification of seven metabolites of a water-soluble platelet aggregation inhibitor in rat urineTANAKA, M; ISHIKAWA, F; HAKUSUI, H et al.Xenobiotica (London. Print). 1995, Vol 25, Num 11, pp 1247-1257, issn 0049-8254Article

In vitro metabolism of nefiracetam by liver microsomes from rats, dogs and monkeysFUJIMAKI, Y; SUDO, K; HAKUSUI, H et al.Arzneimittel-Forschung. 1995, Vol 45, Num 7, pp 748-752, issn 0004-4172Article

Radioimmunoassay for DS-4574, an antiallergic agent : development, evaluation, and application to human plasma samplesMURAYAMA, N; NAKAOKA, M; NOMURA, H et al.Journal of pharmaceutical sciences. 1994, Vol 83, Num 11, pp 1574-1577, issn 0022-3549Article

Identification of a dithiol intermediate metabolite of malotilate in ratsNAKAOKA, M; SUZUKI, W; HAKUSUI, H et al.Xenobiotica (London. Print). 1990, Vol 20, Num 1, pp 91-98, issn 0049-8254Article

Isolation and characterization of a new thio-glucuronide, a biliary metabolite of malotilate in ratsNAKAOKA, M; HAKUSUI, H; TAKEGOSHI, T et al.Xenobiotica (London. Print). 1989, Vol 19, Num 2, pp 209-216, issn 0049-8254Article

Effects of pantoprazole on xenobiotic metabolizing enzymes in rat liver microsomes : A comparison with other proton pump inhibitorsMASUBUCHI, N; HAKUSUI, H; OKAZAKI, O et al.Drug metabolism and disposition. 1997, Vol 25, Num 5, pp 584-589, issn 0090-9556Article

Determination of a new fluoroquinolone antimicrobial agent, (S)-10-[(S)-(8-amino-6-azaspiro[3,4]octan-6-yl)]-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid hemihydrate, DV-7751a, in human serum and urine using solid-phase extraction and high-performance liquid chromatography with fluorescence detectionTANAKA, M; OSHIMA, Y; AOKI, H et al.Journal of chromatography. B, Biomedical applications. 1995, Vol 664, Num 2, pp 401-407Article

Metabolism of irinotecan to SN-38 in a tissue-isolated tumor modelATSUMI, R; OKAZAKI, O; HAKUSUI, H et al.Biological & pharmaceutical bulletin. 1995, Vol 18, Num 7, pp 1024-1026, issn 0918-6158Article

Simultaneous determination of nefiracetam and its metabolites by high-performance liquid chromatographyFUJIMAKI, Y; SUDO, K; HAKUSUI, H et al.Journal of chromatography. Biomedical applications. 1992, Vol 575, Num 2, pp 261-268, issn 0378-4347Article

Species-related stereoselective disposition of ofloxacin in the rat, dog and monkeyOKAZAKI, O; KURATA, T; HAKUSUI, H et al.Xenobiotica (London. Print). 1992, Vol 22, Num 4, pp 439-450, issn 0049-8254Article

High-performance liquid chromatographic determination of (S)-(-)-ofloxacin and its metabolites in serum and urine using a solid-phase clean-upOKAZAKI, O; AOKI, H; HAKUSUI, H et al.Journal of chromatography. Biomedical applications. 1991, Vol 563, Num 2, pp 313-322, issn 0378-4347Article

Stereoselective glucuronidation of ofloxacin in rat liver microsomesOKAZAKI, O; KURATA, T; HAKUSUI, H et al.Drug metabolism and disposition. 1991, Vol 19, Num 2, pp 376-380, issn 0090-9556Article

Pharmacokinetics of midaglizole, a new hypoglycaemic agent, in healthy subjectsNOMURA, H; YAMADA, F; HAKUSUI, H et al.Biopharmaceutics & drug disposition. 1990, Vol 11, Num 8, pp 701-713, issn 0142-2782, 13 p.Article

Quantitation of a new hypoglycaemic drug, 2-[2-(4,5-dihydro-1H-imidazol-2-yl)-1-phenylethyl pyridine dihydrochloride sesquihydrate (DG-5128), in plasma by gas chromatography-mass spectrometryNAKAOKA, M; OHTANI, A; HAKUSUI, H et al.Journal of chromatography. 1986, Vol 378, Num 2, pp 467-472, issn 0021-9673Article

Effects of proton pump inhibitors on thyroid hormone metabolism in rats : a comparison of UDP-glucuronyltransferase inductionMASUBUCHI, N; HAKUSUI, H; OKAZAKI, O et al.Biochemical pharmacology. 1997, Vol 54, Num 11, pp 1225-1231, issn 0006-2952Article